Citrobacter diversus ULA-27 β-lactamases. Improved purification and general properties

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Citrobacter diversus ULA-27 beta-lactamases. Improved purification and general properties.

Two chromosome-encoded beta-lactamases have been purified from Citrobacter diversus ULA-27. They exhibited slightly different isoelectric points (6.8 and 6.2) and very similar Mr values (congruent to 29,000). Their specificity spectrum was rather wide, since they hydrolysed some cephalosporins with kcat: values similar to those observed with the best penicillin substrates. Cloxacillin, methicil...

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Chromosome - encoded f - lactamases of Citrobacter diversus

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1988

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj2540885